Code:

EncoderParameter compressionParam = new EncoderParameter(Encoder.Compression, EncoderValue.CompressionRle);
            
ImageCodecInfo tiffCodec = GetEncoderInfo("image/tiff");

EncoderParameters encoderParams = new EncoderParameters(1);
encoderParams.Param[0] = compressionParam;

img.Save(path, tiffCodec, encoderParams);