Code:

 //Crops Image
    public static void CropImageFile(string ImageFrom, string ImageTo, int targetW, int targetH)
    {
        System.Drawing.Image imgPhoto = System.Drawing.Image.FromFile(ImageFrom);
        int targetX = (imgPhoto.Width - targetW) / 2;
        int targetY = (imgPhoto.Height - targetH) / 2;

        Bitmap bmPhoto = new Bitmap(targetW, targetH, PixelFormat.Format48bppRgb);
        bmPhoto.SetResolution(72, 72);
        Graphics grPhoto = Graphics.FromImage(bmPhoto);
        grPhoto.SmoothingMode = SmoothingMode.AntiAlias;
        grPhoto.InterpolationMode = InterpolationMode.HighQualityBicubic;
        grPhoto.PixelOffsetMode = PixelOffsetMode.HighQuality;
        grPhoto.DrawImage
                (
                imgPhoto,
                new Rectangle(0, 0, targetW, targetH),
                targetX,
                targetY,
                targetW,
                targetH,
                GraphicsUnit.Pixel
                );
        // Save out to memory and then to a file.  We dispose of all objects to make sure the files don't stay locked.
        EncoderParameters ep = new EncoderParameters(1);
        ep.Param[0] = new EncoderParameter(Encoder.Quality, (long)100);

        ImageCodecInfo ici = GetEncoderInfo("image/jpeg");

        imgPhoto.Dispose();
        grPhoto.Dispose();

        bmPhoto.Save(ImageTo, ici, ep);
        bmPhoto.Dispose();
    }

    //CodecInfo
    private static ImageCodecInfo GetEncoderInfo(String mimeType)
    {
        int j;
        ImageCodecInfo[] encoders;
        encoders = ImageCodecInfo.GetImageEncoders();
        for (j = 0; j < encoders.Length; ++j)
        {
            if (encoders[j].MimeType == mimeType)
                return encoders[j];
        }
        return null;
    }